20世紀70年代發現核磁共振（MRI）以來，其應
用在近30年間得到飛速發展，目前它已成為現代社會
無傷害性醫學成像技術中最為重要的技術之一。隨著
神經科學的迅速發展，20世紀90年代初功能性核磁共
振（fMRI）被引入，並成為當今探索大腦活動最有價
值的工具之一。楊可人編著的《高時間分辨功能成像
(英文版)》詳細介紹了核磁共振、功能性核磁共振的
成像原理及應用方法。
成像的速度是核磁共振重要的衡量指標，
Multiband（MB）成像是前沿的高時間分辨率成像技
術，可用於同時采集多層圖像。本書將介紹
Multiband成像原理及其3個應用，具體包括靜態功能
性核磁共振（resting-state fMRI）、軀體感覺區
功能性核磁共振（somatosensory fMRI）和磁共振
動脈自旋標（ASL）。

Abstract
Acknowledgements
1 Introduction
1.1 Comparison between the MRI and others
1.2 Overview of the book
2 Nuclear magnetic resonance and magnetic resonance imaging
2.1 NMR
2.1.1 Introduction
2.1.2 Nuclei and spin, energy levels
2.1.3 Spins in magnetic eld
2.1.4 Boltzmann statistics
2.1.5 Rotating frame
2.1.6 Relaxation
2.1.7 Bloch equation
2.1.8 Chemical shift
2.2 MRI
2.2.1 Introduction
2.2.2 Gradients
2.2.3 Slice selection
2.2.4 Spatial encoding
2.2.5 k-space
2.2.6 Gradient echo imaging
2.2.7 Spin echo imaging
2.2.8 Echo planar imaging
2.2.9 Turbo spin echo imaging
2.2.10 GRASE
2.2.11 Parallel imaging
2.2.12 Simulation of matrix inversion
2.3 Hardware
2.3.1 Overview
2.3.2 Main magnet
2.3.3 Shim coils
2.3.4 Gradient coils
2.3.5 RF system
Bibliography
3 Functional magnetic resonance imaging
3.1 Introduction
3.2 Cerebral cortex
3.2.1 Somatosensory cortex
3.2.2 Motor cortex
3.2.3 Visual cortex
3.3 BOLD contrast
3.4 fMRI data acquisition
3.5 Paradigm
3.6 Data analysis
3.6.1 Preprocessing
3.6.2 Statistical analysis
3.7 Cortical flattening
3.8 Resting state
3.9 Perfusion imaging
3.10 Conclusion
Bibliography
4 A comparison of resting state functional connectivity
using fast imaging: 2D GEEPI, 3D GEEPI and 3D PRESTO
4.1 Introduction
4.1.1 Brain networks
4.1.2 Default mode network （DMN）
4.1.3 Sensorimotor network
4.1.4 Visual network
4.1.5 Dorsal attention network
4.2 Overview of fast imaging sequences
4.2.1 Echo planar imaging
4.2.2 PRESTO
4.3 Methods
4.3.1 Data acquisition
4.3.2 Data analysis
4.4 Results
4.4.1 No physiological noise correction
4.4.2 Post physiological correction
4.5 Discussion
4.6 Conclusion
Bibliography
5 Implementation and application of multiband echo planar
imaging in conjunction with SENSE
5.1 Introduction
5.2 Multiband imaging
5.2.1 Introduction
5.2.2 Multiband RF pulses
5.2.3 Optimization
5.2.4 Reconstruction
5.3 Implementation
5.4 Applications
5.4.1 Resting state fMRI
5.4.2 Somatotopic mapping of both primary and secondary somatosensory cortex
5.4.3 Multiband DABS ASL
5.5 Conclusion
Bibliography
6 Orientation mapping at ultra-high field
6.1 Visual cortex
6.2 Retinotopic organization
6.3 Orientation column organization
6.4 Introduction to the study
6.5 Methods
6.5.1 Stimuli and paradigm
6.5.2 fMRI data acquisition
6.5.3 Pre-processing
6.5.4 Data analysis
6.6 Results
6.7 Discussion
6.8 Conclusion
Bibliography
Abbreviations
Index