全球當今青蒿素及其衍生物，無論單藥或者復方
，無論中國或者外國生產，無一不是中國人發明的。
Li Guoqiao，Ying Zelin，Zeng Meiyi編著的《青
蒿素類抗瘧藥（英文版）》記錄了青蒿素類抗瘧藥的
發明全過程和詳盡的研究數據，為我國在新藥發明史
上留下一份既全面又真實的珍貴文獻。同時本書既有
中國40年來相關的研究結果，又涵蓋了近年國際上的
最新發展有較高的學術價值。本書首先闡述發明歷史
和研發思路（以原始資料為據），然後按植物學、化
學、藥物分析、藥理毒理學、青蒿素類藥各種制劑的
臨床研究和應用等繫統闡述，先單藥後復方。

The Development of Qinghaosu (Artemisinin) - A View From the Outside
Foreword - Sun Manji
Foreword - Keith Arnold
Preface
Introduction
1.Discovery of Qinghaosu (Artemisinin)--History of Research and Develoment of Artemisinin-Based Antimalarials
1.1 Discovery of Artemisinin and Early Antimalarial Research
A.The Discovery of Qinghaosu(Artemisinin)
B.Nationwide Collaboration on Artemisinin Research in Treating Malaria
C.Project Validation and the National Invention Award
1.2 The Development of Artemisinin and Its Derivatives asAntimalarials
A.Artemisinin
B.Artemether
C.Artesunate
D.Dihydroartemisinin
1.3 Innovation of Artemisinin-Based Combinations
A.Artemether-Lumefantrine Combination (Coartem)
B.Artemisinin-Naphthoquine Phosphate Combination (ARCO)
C.Artemisinins-Piperaquine Combinations (CV8, Artekin,Duo-Cotexin, Artequick)
1.4 China's Research Program Under the Chinese Steering Committee for Research of Qinghaosu and Its Derivatives
A.WHO Interested in China's Artemisinin Antimalarials
B.The Chinese Steering Committee for Qinghaosu Research and Its Tasks
C.Joint Projects Between the Chinese Steering Committee for Qinghaosu Research and WHO/TDR
D.Raising the Standards of New-Drug Research and Production Specifications
E.Surveys into Artemisia annua Linnaeus Resources and a Base for Artemisinin Production
F.Preparing for the Global Market
G.Termination of the Chinese Steering Committee for Qinghaosu Research
1.5 Management of Artemisinin Antimalarial Projects
A.Clear Direction and Goals
B.Forward-Looking Innovation
C.New Centralized Management
D.Mutual Aid and Strength in Numbers
E.Respecting Knowledge and Talent
References
2.Agronomics and Biology of Artemisia annua L.
2.1 Propagation and Cultivation ofArtemisia annua
A.Botanical and Medicinal Properties
B.Resource Distribution and Origin
C.Propagation
D.Cultivation
2.2 Cellular Engineering ofArtemisia annua
A.Overview of Tissue and Organ Culturing
B.Hairy Root Cultures
C.Induction of Shoot Clusters
D.Hairy Roots and Adventitious Shoots Cultured in Bioreactors
E.Establishment of Genetic Transformation System
2.3 Biosynthetic Pathways and Bioengineering of Artemisinin
A.Biosynthetic Pathways
B.Genes Involved in Biosynthesis
C.Regulation of Artemisinin Biosynthesis