內容介紹 | |
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出版社:科學
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ISBN:9787030440983
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作者:KWOK-FAI SO//XIAO-MING XU
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頁數:431
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出版日期:2015-01-01
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印刷日期:2015-01-01
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包裝:精裝
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開本:16開
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版次:1
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印次:1
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神經科學是二十一世紀發展最為活躍的學科,神 經再生則是神經科學中最具潛力的領域之一,揭示神 經損傷後再生的奧秘和機制,其影響將遠超出神經科 學的範疇。KWOK-FAI SO、XIAO-MING XU主編的這本 《神經再生(英文版)》以近年來神經科學新進展為 指導,收集國內外最新神經再生研究資料並結合編寫 者各自的研究成果,從形態與結構、組織與功能、分 子與蛋白、干細胞與組織工程、基礎與臨床等角度, 對神經再生進行較為繫統、深入的闡述。
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List of Contributors I. INTRODUCTION 1. Advances and Challenges for Neural Regeneration Research XIAOFEI WANG, KWOK-FAI SO, XlAO-MING XU 1. Nervous System, Nerve Injury, and Neural Regeneration 2. Technological Advances in Neural Regeneration Research 3. PNS Regeneration 4. CNS Regeneration 5. Challenges and Opportunities Acknowledgments References II. NEURAL REGENERATION IN LOWER VERTEBRATES 2. Functional Regeneration and Remyelination in the Zebrafish Optic Nerve SU.QI zou, wu YIN, YU-B1N HUANG, CHEN TIAN, SHU-CHAO GE, BING HU 1. Introduction to Zebrafish Optic Nerve Injury (ONI) as a Model for Studying Regeneration and Remyelination 2. Time Course of Optic Nerve Regeneration in Adult Zebrafish 3. Intrinsic and Extrinsic Mechanisms of Axon Regeneration 4. Genetic Manipulation Tools are Very Useful for Studying Regeneration in Zebrafish 5. In vivo Imaging of Nerve Regeneration in Zebrafish Larvae 6. Imaging Remyelination in Zebrafish 7. Behavior Tests Indexed the Visual Functional Recovery after Optic Nerve Injury 8. Future Directions 9. Conclusions Acknowledgments References 3. Central Nerve Regeneration in Reptiles JENNIFER RODGER, SARAH A. DUNLOP 1. Introduction 2. Timing of Regeneration--General Compared to Fish and Frogs, Including Geckos, etc. 3. Retinal Ganglion Cell Survival 4. Glia: Friend or Foe? 5. Growth Promotion: Neurotrophins, Extracellular Matrix, Gefiltin, Polysialic Acid-Neural Cell Adhesion Molecule, Comparison with Development 6. Topography and Refinement: NMDA/AMPA/GABA and Synaptic Proteins 7. Conclusion: Relevance to Mammals 8. Conclusions Acknowledgments References 4. Axon Regeneration in the Lamprey Spinal Cord MICHAEL I. SH1FMAN, MICHAEL E. SELZER 1. The Need for Lower Vertebrate Models of Axon Regeneration in the Central Nervous System 2. General Biology of the Lamprey 3. The Central Nervous System of the Sea Lamprey 4. Anatomical and Functional Evidence for Axon Regeneration in the Lamprey Spinal Cord 5. Is Axon Regeneration a Recapitulation of Axon Development? 6. Neuron-Intrinsic Determinants of Axon Regeneration 7. Conclusions References III. NEURAL REGENERATION IN THE PERIPHERAL NERVOUS SYSTEM 5. Tissue Engineering in Peripheral Nerve Regeneration XIAOSONG GU, FEI D1NG, YUMIN YANG, JIE LIU 1. Introduction 2. Nerve Scaffolds 3. Support Cells 4. Growth Factors 5. Clinical Applications 6. Concluding Remarks References 6. Brachial Plexus Avulsion: A Model for Axonal Regeneration Study HUANXING SU, QIUJU YUAN, LIHUA ZHOU, WUTIAN WU 1. Anatomy of Human and Rodent Brachial Plexus 2. Brachial Plexus Avulsion …… IV. NEURAL REGENERATION IN THE CNS V. TRANSPLANTATION-MEDIATED NEURAL REGENERATION VI. CLINICAL AND TRANSLATIONAL RESEARCH ON NEURAL REGENERATION Index
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