吳巍、張玉祥主編的《分子生物學》為“醫學教
育改革繫列教材”（英文版）之一。
分子生物學是從分子水平上研究生命現像物質基
礎的學科。《分子生物學》繫統論述細胞成分的物理
、化學的性質和變化以及這些性質和變化與生命現像
的關繫，如遺傳信息的傳遞，基因的結構、復制、轉
錄、翻譯、表達調控和表達產物的生理功能，以及細
胞信號的轉導等。本教材主要面向在我國接受醫學教
育的海外留學生和接受雙語教學的本科生。

Chapter 1 Historical Review of Molecular Biology
1.1 Definition of Molecular Biology
1.2 Brief History of Molecular Biology
1.3 Basic Content of Molecular Biology
1.4 Role of Molecular Biology in Medical Science
Chapter 2 Transmission of Genetic Information
2.1 DNA Replication
2.2 Transcription
2.3 Translation
Chapter 3 Gene Regulation
3.1 Gene Regulation in Prokaryotes
3.2 Gene Regulation in Eukaryotes
3.3 Noncoding RNA and RNA Interference
3.4 Epigenetic Regulation of Gene Expression
3.5 Gene Regulatory Network
Chapter 4 DNA Damage and Repair
4.1 Factors Causing DNA Damage
4.2 Types of DNA Damage
4.3 DNA Repair Mechanisms
4.4 DNA Damage Caused Effects
Chapter 5 Protein Modification, Trafficking and Degradation
5.1 Folding of Nascent Polypeptide Chains
5.2 Assembly of Protein Subunits
5.3 Posttranslational Modifications of Proteins
5.4 Transport and Localization of Proteins
5.5 Degradation of Cellular Proteins
5.6 Clinical Significance of Protein Modification, Trafficking and Degradation
Chapter 6 Molecular Cloning and Genetic Engineering
6.1 Cloning Enzymes
6.2 Cloning Vectors
6.3 Principle and Procedures of Molecular Cloning
6.4 Genetic Engineering
Chapter 7 Gene Characterization and Functional Analysis
7.1 Nucleic Acid Molecular Hybridization
7.2 Polymerase Chain Reaction
7.3 Nucleic Acid Sequencing
Chapter 8 Omics and System Biology
8.1 Genomics
8.2 Transcriptomics
8.3 Proteomics
8.4 Metabolomics
Chapter 9 Gene Transfer and Gene Targeting
9.1 Gene Recombination
9.2 Gene Transfer and Transgenic
9.3 Gene Targeting by Homologous Recombination
9.4 Transgenic and Its Application
Chapter 10 Molecular Biology of Cancer
10.1 Cell Cycle and Apoptosis
10.2 Oncogenes and Tumor Suppressor Genes
10.3 Molecular Basis of Cancer Development